Tonic VIP neurons terminated at a reliable pace with similarly spaced intervals between each firing show and VIP abnormal neurons terminated in doublets or triplets with similarly spaced intervals after every doublet or triplet. The experts then tested whether activation of VIP neurons would shift the daily routine from the SCN as well as the mice. To carry out the experiment, research workers kept mice altogether darkness all day long and forever without environmental clues in what time it had been. Using a device called optogenetics, they turned on just the VIP neurons at exactly the same time every time, an operation that mimicked traveling to a fresh time zone. ‘This was a significant step to comprehend the way the SCN helps to keep organisms synced with their local light timetable,’ Mazuski stated.